Anti-Ms CD8a, 53-6.7, PE, 50µg

A PE-conjugated rat monoclonal antibody from STEMCELL Technologies, Clone 53-6.7 is directed against mouse CD8a, a 32 - 34 kDa type I transmembrane glycoprotein that forms a subunit of CD8. According to the manufacturer, the clone is verified for cell isolation and flow cytometry, and is referenced within immunomagnetic positive selection and negative isolation protocols for mouse T cell populations.

The third-party product sheet describes CD8a as acting as a co-receptor to the T cell receptor during T cell activation by binding MHC Class I molecules, and reports that Clone 53-6.7 reportedly blocks antigen presentation via MHC class I and inhibits IL-2-dependent T cell responses. The reagent is an IgG2a, kappa isotype antibody.

Provided as a clear liquid laboratory reagent, the product is not classified as hazardous under the OSHA Hazard Communication Standard (29 CFR 1910.1200). The manufacturer states that products are for research use only and are not intended for human or animal diagnostic or therapeutic uses unless otherwise stated, and that the quality management system is certified to ISO 13485.