Anti-Ms CD24, M1/69, PS, 100µg

A rat monoclonal IgG2b, kappa antibody from STEMCELL Technologies, Clone M1/69 recognizes murine CD24, a glycoprotein of approximately 35 - 45 kDa expressed on lymphocytes, granulocytes, thymocytes, erythrocytes, epithelial cells, neurons, and dendritic cells.

CD24 is differentially expressed during T and B cell development and is not found on the majority of mature peripheral T cells or plasma cells. It is expressed on pro-B, pre-B and mature B cells, but expression is strongly down-regulated after B cell activation. The protein is involved in regulating B-cell apoptosis and in preventing terminal differentiation of B cells into antibody-secreting plasmablasts and plasma cells, and acts as an adhesion or co-stimulatory molecule in lymphocyte activation, proliferation and differentiation through homophilic interactions or by binding to ligands such as P-selectin (CD62P).

The PerCP-Cy5.5-conjugated format has been validated by flow cytometry analysis of C57BL/6 mouse splenocytes. The product is supplied as a clear liquid that is stable under recommended transport and storage conditions, and is intended for use as a laboratory reagent; refer to the Product Information Sheet for handling and storage guidance.