Anti-Ms CD24, M1/69, AD, 25µg

The M1/69 monoclonal antibody from STEMCELL Technologies reacts with murine CD24, an approximately 35 - 45 kDa glycoprotein expressed on lymphocytes, granulocytes, thymocytes, erythrocytes, epithelial cells, neurons, and dendritic cells. CD24 is differentially expressed during T and B cell development and is not found on the majority of mature peripheral T cells or plasma cells. It is expressed on pro-B, pre-B, and mature B cells, with expression strongly down-regulated after B cell activation.

This clone is provided conjugated to Alexa Fluor® 488 and is intended for use in flow cytometry. It is raised in rat and has an IgG2b, kappa isotype. CD24 is involved in regulating B-cell apoptosis and in preventing terminal differentiation of B cells into antibody-secreting plasmablasts and plasma cells. It also acts as an adhesion or co-stimulatory molecule and participates in lymphocyte activation, proliferation, and differentiation through homophilic interactions or by binding to ligands such as P-selectin (CD62P).

According to the manufacturer's Safety Data Sheet, the conjugate is not classified as a hazardous substance or mixture. The product is for research use only and is not intended for human or animal diagnostic or therapeutic uses.