Anti-Ms CD152, UC10-4F10-11, AZ, 25µg

Purified hamster monoclonal antibody specific for mouse CD152 (CTLA-4), supplied by STEMCELL Technologies as 25 µg in an azide-free formulation enabling downstream conjugation or functional assays. The UC10-4F10-11 clone binds the extracellular domain of cytotoxic T-lymphocyte-associated protein 4, an immune checkpoint receptor upregulated on activated CD4+ and CD8+ T cells and constitutively expressed on regulatory T cell populations. Researchers use this reagent in flow cytometry panels to characterize Treg frequencies, track activation-induced CTLA-4 surface expression, and investigate tolerance and checkpoint blockade mechanisms in murine models. The azide-free buffer preserves cell viability during in vitro assays, and the vial format is convenient for routine experimental work. Each lot is validated to confirm specific recognition of mouse CD152 with minimal cross-reactivity, supporting reproducible staining of lymph node and splenocyte preparations.