Anti-Hu HLA-DR, L243, FI, 500tests

The L243 clone monoclonal antibody specifically recognizes human HLA-DR, a major histocompatibility complex (MHC) class II molecule expressed on antigen-presenting cells including B lymphocytes, monocytes, dendritic cells, and activated T cells. Manufactured by STEMCELL Technologies, this fluorescein (FITC)-conjugated reagent is optimized for multicolor flow cytometry immunophenotyping, enabling researchers to gate MHC II-positive populations in peripheral blood mononuclear cells, splenocytes, and dissociated tissue samples. Each vial supports 500 tests at typical staining volumes, and the direct fluorophore conjugation eliminates secondary antibody incubation steps, reducing assay time and minimizing background signal. The L243 epitope maps to the alpha subunit of the HLA-DR heterodimer and is widely cited in studies of autoimmune disease, transplant immunology, and tumor immune microenvironment characterization. Compatible with standard blue-laser (488 nm) flow cytometers, the reagent pairs well with other fluorochromes in panels targeting T-cell subsets, regulatory populations, and myeloid lineages, supporting reproducible research use only workflows in immunology and cell biology laboratories.