Anti-Hu HLA-DR, L243, FI, 100tests

For immunology and cell biology laboratories investigating MHC class II expression, this FITC-conjugated anti-human HLA-DR antibody from STEMCELL Technologies delivers a validated reagent for flow cytometry-based immunophenotyping. The L243 monoclonal clone binds a monomorphic determinant on the HLA-DR alpha chain, enabling consistent detection of antigen-presenting cells including B lymphocytes, monocytes, macrophages, and dendritic cells.

Supplied as a 100-test vial, the reagent is qualified for use in multicolor panels to enumerate HLA-DR positive populations in peripheral blood mononuclear cells, monitor immune reconstitution after hematopoietic stem cell transplantation, and characterize aberrant class II expression in autoimmune disease studies. The antibody shows no significant cross-reactivity with HLA-DP or HLA-DQ, supporting clean discrimination of HLA-DR expressing subsets in mixed leukocyte cultures.

Researchers preparing samples for flow cytometry can pair this FITC conjugate with PE, APC, or BV405-labeled antibodies to resolve naive, memory, and activated lymphocyte populations. Each lot is QC-tested by STEMCELL Technologies for staining consistency, and the vial should be refrigerated and protected from light to maintain fluorophore performance.