Anti-Hu CD16, 3G8, AD, 25tests

A monoclonal antibody (clone 3G8) conjugated to Alexa Fluor® 488 from STEMCELL Technologies reacts with human CD16, also known as FcγRIII or low affinity IgG receptor III, a type 1 transmembrane glycoprotein belonging to the Ig superfamily. CD16 exists in two isoforms: CD16a, a 50 - 65 kDa form expressed on NK cells, activated monocytes, macrophages, and placental trophoblasts, and CD16b, an ~48 kDa glycosylphosphatidylinositol (GPI)-anchored form expressed on neutrophils, basophils and eosinophils and found as at least two polymorphic variants, termed NA1 and NA2.

The reagent has been verified for flow cytometry and cell separation. Per the manufacturer's safety data sheet, the antibody is supplied as a clear liquid laboratory reagent and is not classified as hazardous under the 2012 OSHA Hazard Communication Standard (29 CFR 1910.1200). STEMCELL Technologies' quality management system is certified to ISO 13485, and the product is intended for research use only, not for human or animal diagnostic or therapeutic uses unless otherwise stated.