Anti-Hu ACE2, AC18F, TO, 100tests

The STEMCELL Technologies Anti-Hu ACE2 antibody (clone AC18F) is a conjugated reagent for flow cytometry detection of human angiotensin-converting enzyme 2 on cell surfaces. ACE2 functions as the principal host-cell entry receptor for SARS-CoV-2, positioning this reagent as a standard tool in coronavirus entry research, viral tropism studies, and characterization of permissive cell populations.

Supplied as a 100-test vial, the conjugate is configured for direct immunofluorescence staining of live or fixed cell suspensions. Researchers apply the reagent to detect surface ACE2 expression on epithelial lines such as Calu-3 and Vero E6, primary airway organoid cultures, and peripheral blood subsets. Stained samples are acquired on flow cytometry instruments, with signal intensity interpreted against isotype and unstained controls to quantify receptor density per cell.

Beyond receptor profiling, this antibody supports spike-protein pseudovirus neutralization assays, CRISPR-mediated ACE2 knockout validation, and screening of small-molecule or antibody candidates that modulate viral entry. Each lot is validated for specificity against human ACE2 with minimal off-target binding, supporting reproducible downstream workflows in immunology, virology, and cell biology laboratories.