Simian Annexin A5 (ANXA5) ELISA Kit

The Simian ANXA5 immunoassay from Assay Genie is a quantitative enzyme-linked immunosorbent assay formatted for non-human primate research, supporting studies of apoptosis and annexin-mediated phospholipid binding in macaque, cynomolgus, and related simian models. The kit accepts various liquid sample types collected during preclinical pharmacology, vaccine safety evaluation, and toxicology workflows, where Annexin A5 serves as a circulating indicator of phosphatidylserine exposure and programmed cell death.

Each kit contains pre-coated microplate wells, matched antibody reagents, calibration standards, and detection components sufficient to run 96 individual determinations. The procedure follows a sequential incubation workflow: capture antibody is immobilized on the plate, standards or unknowns are added, and a conjugated detection antibody binds the captured analyte to generate an absorbance signal proportional to ANXA5 concentration. Plates are read on a standard microplate reader equipped for visible-wavelength measurement.

Researchers use this reagent to profile baseline Annexin A5 levels in simian cohorts, monitor changes following experimental intervention, and compare results against published reference data for cynomolgus and rhesus macaques. Typical applications include infectious disease research, cardiovascular safety pharmacology, and reproductive or developmental studies that require a simian-reactive quantitative readout. Reagents are supplied in single-use vials and should be stored refrigerated to preserve antibody activity; allow kit components to equilibrate to room temperature before opening, and avoid repeated freeze-thaw cycles of working standards. For research use only.