Rat XOD (Xanthine Oxidase) ELISA Kit (RTES01195)

Xanthine oxidase (XOD) is a molybdenum-containing enzyme central to purine catabolism, catalyzing the sequential oxidation of hypoxanthine to xanthine and then to uric acid while generating reactive oxygen species such as superoxide and hydrogen peroxide. The Rat XOD ELISA Kit from Assay Genie offers an in vitro immunoassay for quantitative measurement of this enzyme in rat-derived samples, supporting investigations of oxidative stress, gout pathogenesis, ischemia-reperfusion injury, and related inflammatory pathways.

Rodent model studies in cardiovascular, renal, and metabolic disease research rely on accurate XOD quantification to evaluate enzyme dysregulation in hyperuricemia, assess the efficacy of xanthine oxidase inhibitors such as allopurinol and febuxostat, and characterize antioxidant interventions targeting ROS-mediated cellular damage. Common applications include profiling XOD expression in liver, kidney, lung, and vascular endothelium across treatment cohorts, as well as tracking enzyme conversion between the dehydrogenase and oxidase forms under hypoxic conditions.

Supplied as a complete kit with a well-plate format suitable for medium-throughput screening, the assay yields a measurable colorimetric signal readable on standard microplate readers. The workflow accommodates standard laboratory protocols for protein quantification in preclinical research and is intended for research use only, not for diagnostic or clinical procedures.