Rat XIAP (X-Linked Inhibitor Of Apoptosis Protein) ELISA Kit (RTES00890)

XIAP, or X-linked Inhibitor of Apoptosis Protein, sits at a critical node in the intrinsic apoptosis cascade, binding and inhibiting caspase-3, caspase-7, and caspase-9. Its quantitative profiling in rat model systems supports research into oncology, neurodegeneration, ischemia-reperfusion injury, and toxicology, where shifts in IAP-family expression often signal altered cell-survival dynamics. This immunoassay from Assay Genie is configured to detect rat XIAP across multiple sample matrices commonly prepared in apoptosis-focused laboratories.

The kit ships as a complete reagent package built around a pre-coated microplate and is intended for in vitro research use only. Researchers typically aliquot reagents upon receipt, store working stocks at 4°C, and reserve long-term aliquots at -20°C to preserve antibody and standard integrity across multiple freeze-thaw cycles. Standard curves are generated from a provided recombinant XIAP calibrator series, and absorbance readings are taken on a standard microplate reader to quantify endogenous XIAP across experimental conditions.

This product supports investigations into IAP-family expression changes triggered by pharmacological agents, disease progression, or genetic manipulation of upstream apoptotic regulators in rat model systems. The targeted rat reactivity makes it useful for longitudinal studies that compare XIAP levels across treatment cohorts, genetic backgrounds, or defined disease-progression time points, helping laboratories link IAP signalling to downstream caspase activity and cell fate decisions.