Rat Von Hippel Lindau Tumor Suppressor (vHL) ELISA Kit

The VHL (Von Hippel-Lindau) tumor suppressor protein functions as the substrate recognition component of an E3 ubiquitin ligase complex that targets hydroxylated HIF-alpha subunits for proteasomal degradation under normoxic conditions. This rat-specific quantitative ELISA from Assay Genie enables precise measurement of VHL protein in tissue homogenates and biological fluids, supporting investigations into clear cell renal cell carcinoma, hemangioblastoma, pheochromocytoma, and inherited VHL disease models. Recommended sample volume is 50 µL per well, with the assay showing rat-specific detection and no significant cross-reactivity with mouse or human VHL orthologs. Each microplate provides 96 assays in a sandwich format with colorimetric readout, and protocol steps are consistent with standard research ELISA workflows. Reagents should be refrigerated and protected from light; the kit is restricted to in vitro research use only, not for diagnostic or clinical applications.