Rat Vesicular acetylcholine transporter/SLC18A3 ELISA Kit

This colorimetric sandwich ELISA kit from Assay Genie enables quantitative detection of the rat Vesicular Acetylcholine Transporter (SLC18A3) in serum and plasma samples. Also known by synonyms including VAChT, Vacht, and solute carrier family 18 member 3, this multi-pass membrane protein is responsible for transporting acetylcholine into synaptic vesicles, a critical step in neurotransmitter release and nerve signal transmission. Dysregulation of this transporter has been implicated in various neurological disorders, making it a valuable biomarker for research applications.

The assay is validated for use with serum, plasma, tissue homogenates, cell culture supernatants, and other biological fluids, and specifically detects natural and recombinant rat Vesicular acetylcholine transporter. With a detection range of 0.625–40 ng/mL and a sensitivity of 0.312 ng/mL, the kit provides precise and reproducible results. Precision is characterized by an intra-assay CV of 4.9% and inter-assay CV of 8.5%. The kit is intended for research use only and includes all necessary reagents and components for the assay procedure.