Rat Valosin Containing Protein (VCP) ELISA Kit

VCP, also called p97 or Cdc48, is a highly conserved AAA+ ATPase that fuels ubiquitin-dependent protein degradation and endoplasmic reticulum-associated degradation. It forms a hexameric ring that unfolds client proteins and shuttles them to the proteasome. Dysregulated VCP activity is implicated in inclusion body myopathy with Paget disease, frontotemporal dementia, amyotrophic lateral sclerosis, and certain cancers, so quantitative measurement in rat tissues supports research into proteostasis, neurodegeneration, and muscle wasting models.

The Assay Genie kit arrives as a complete set of pre-coated microplate wells, capture antibody, detection antibody, standards, and substrate reagents for 96 determinations. Reconstitute reagents as directed in the product insert, aliquot unused portions to limit freeze-thaw cycles, and store components refrigerated while protected from light to preserve activity across the assay workflow.