Rat TWEAK R PharmaGenie ELISA Kit (SBRS1706)

Quantify TWEAK receptor (TNFRSF12A/Fn14) levels in rat samples with this 96-assay enzyme-linked immunosorbent kit from Assay Genie. The assay is calibrated specifically for rat TNFRSF12A and accepts cell culture supernatants, plasma, and serum, supporting research on the TWEAK/Fn14 signaling axis in cardiovascular, renal, and inflammatory disease models.

TWEAK R is a small type I transmembrane protein of the TNF receptor superfamily. On ligand binding by TWEAK (TNFSF12), it recruits TRAF2 and activates NF-κB, driving proliferation, migration, and pro-inflammatory cytokine release. Fn14 expression rises sharply after tissue injury, so researchers monitoring rat models of stroke, kidney damage, liver repair, or metabolic dysfunction use receptor-level measurements as a readout of pathway engagement.

Each kit contains a pre-coated microplate, lyophilized standards, biotinylated detection antibody, streptavidin-HRP conjugate, and substrate sufficient for 96 reactions. Intended for research use only.