Rat TrxR1 (Thioredoxin Reductase 1) ELISA Kit (RTES00794)

The Rat TrxR1 ELISA Kit from Assay Genie provides researchers with a quantitative immunoassay for measuring cytosolic Thioredoxin Reductase 1, a selenocysteine-containing homodimeric flavoenzyme of approximately 55 kDa per subunit, central to cellular redox homeostasis. TrxR1 drives the NADPH-dependent reduction of thioredoxin, fueling ribonucleotide reductase activity for DNA synthesis and supporting antioxidant defense against reactive oxygen species. Because TrxR1 expression is frequently upregulated in tumors and altered in neurodegenerative and inflammatory states, the kit supports studies in cancer biology, oxidative stress research, and pharmacology, including work on TrxR1 inhibitors such as auranofin and other gold-based compounds. Validated liquid sample matrices include serum-derived and plasma-derived preparations, with the microplate format intended for research use only. Reagents should be stored refrigerated and protected from light; consult the kit insert for shelf life and freeze-thaw guidance.