Rat TIM-1 PharmaGenie ELISA Kit (SBRS1699)

A phosphatidylserine-binding receptor central to nephrotoxicology and immune regulation research, rat TIM-1 (also known as HAVCR1, the hepatitis A virus cellular receptor 1) is quantified by this Assay Genie immunoassay across conditioned media from cultured cells, plasma, and serum drawn from experimental animals. The 96 assays strip-well plate format uses a two-antibody capture approach, with results interpreted from a standard curve generated from the included rat TIM-1 reference reagents.

Investigators apply the kit to renal injury biomarker studies tracking KIM-1/HAVCR1 expression along proximal tubules, immune checkpoint work profiling costimulatory signalling on T helper subsets, and translational projects examining hepatitis A virus entry. Rat TIM-1 is a type I transmembrane glycoprotein expressed on activated lymphocytes, polarized kidney epithelium, and select antigen-presenting populations; its shed ectodomain circulates at concentrations that report tubular damage in nephrotoxicity and islet allograft rejection models. Endpoints are captured on a microplate reader measuring absorbance, for in vitro research use.