Rat TFF2/Trefoil factor 2 ELISA Kit

Assay Genie offers a sandwich-format ELISA Kit for the quantitative detection of rat Trefoil factor 2 (TFF2). The assay is reactive with rat samples and has been validated for use with serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. Detection is performed using a colorimetric method, and the kit is intended for research use only, supporting work in the signal transduction research area.

Performance characteristics include a detection range of 0.156-10ng/mL and a sensitivity of 0.078ng/mL. Specificity is reported for both natural and recombinant rat Trefoil factor 2. TFF2 is also referred to by the synonyms Spasmolytic polypeptide (SP) and Sml1, and the target protein corresponds to UniProt accession Q09030. The protein is localized to the secreted compartment of the cell.

According to UniProt data, TFF2 inhibits gastrointestinal motility and gastric acid secretion, and may serve as a structural component of gastric mucus by stabilizing glycoproteins through interactions with carbohydrate side chains. NCBI describes it as a member of the trefoil family characterized by the trefoil motif, potentially contributing to gastric mucosal structure and regulation of acid secretion.