Rat Spondin-2 (Spon2) ELISA Kit

Manufactured by Assay Genie, this Sandwich ELISA Kit is designed for the quantitative detection of Spondin-2 (SPON2) levels in rat serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. Reactivity is rat, and the kit specifically recognizes natural and recombinant rat Spondin-2. Performance figures include a detection range of 78-5000pg/mL and a sensitivity of 39.3pg/mL.

The target protein, Spondin-2 (synonym: Mindin; UniProt Q9WV75), is described as a cell adhesion protein that promotes adhesion and outgrowth of hippocampal embryonic neurons. It binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria, and is described as essential in the initiation of the innate immune response and as a pattern-recognition molecule in the ECM for microbial pathogens. The protein is a monomer that interacts with integrin and is localized to the secreted extracellular space and extracellular matrix. The associated research area is immunology. The kit is for research use only.