Rat Sorbitol Dehydrogenase (SDH) ELISA Kit

Sorbitol dehydrogenase (SDH) is a cytosolic enzyme that catalyzes the NAD⁺-dependent interconversion of D-sorbitol and D-fructose within the polyol pathway, a route of particular interest in diabetes research, hepatic carbohydrate metabolism, and reproductive biology where SDH expression in spermatozoa and accessory tissues is notable. The Rat Sorbitol Dehydrogenase ELISA Kit from Assay Genie provides researchers with a quantitative tool for measuring this enzyme across rat-derived biological specimens, supporting work in polyol-pathway flux, lens and peripheral nerve studies under hyperglycaemic conditions, and toxicology screens of liver and kidney tissue.

The assay accommodates multiple sample matrices, including whole blood fractions, tissue homogenates prepared from liver or kidney, cell lysates, and clarified cell culture supernatants, giving flexibility across in vivo and in vitro experimental designs. The kit is supplied as a complete package of 96 assays in a microplate format, with all reagents prepared to minimise hands-on time. Unopened kit components should be refrigerated, and reconstituted standards handled according to the enclosed protocol.

Investigators characterising hepatotoxicity, polyol-pathway involvement in diabetic complications such as cataract formation and peripheral neuropathy, or spermatogenesis in rat models can track tissue-specific and circulating SDH levels across treatment groups with this assay. For research use only.