Rat SOCS3 (Suppressors Of Cytokine Signaling 3) ELISA Kit (RTES00771)

Cell signaling studies frequently require quantitative measurement of intracellular regulatory proteins that govern cytokine-driven pathways. The Assay Genie Rat SOCS3 ELISA Kit quantifies Suppressors of Cytokine Signaling 3 in rat samples, supporting research into the JAK-STAT signaling cascade where SOCS3 acts as a feedback inhibitor downstream of receptors for IL-6, leptin, erythropoietin, and growth hormone.

The kit serves investigations into inflammatory feedback loops, hepatic injury models, adipocyte leptin resistance, and central nervous system disorders where dysregulated STAT3 activation has been implicated. It provides 96 assays per microplate with a colorimetric read-out compatible with standard laboratory plate readers set to the appropriate absorbance wavelength.

Typical applications include cytokine signaling studies in rodent models of sepsis, colitis, neuroinflammation, and metabolic disease. Components ship under refrigerated conditions and should be stored refrigerated upon arrival; reconstituted standards and working solutions may require freezing for longer-term stability. Each kit contains pre-coated wells, detection antibodies, standards, and substrate reagents sufficient for 96 individual determinations. Intended for research use only.