Rat SLC5A5 (Solute carrier family 5 member 5) ELISA Kit (RTFI01438)

Used in endocrine research, this quantitative immunoassay from Assay Genie measures the sodium-iodide symporter (NIS), the transmembrane glycoprotein encoded by the SLC5A5 gene that actively transports iodide across the basolateral membrane of thyroid follicular cells. The plate-format kit enables researchers to track NIS expression in rat-derived samples and supports work on thyroid hormone biosynthesis, iodide transport regulation, and the impact of goitrogenic compounds such as perchlorate and thiocyanate that competitively inhibit iodide uptake. Reconstituted standards and detection antibody should be refrigerated, and unopened kit components remain stable under recommended handling conditions. Common applications include investigations of extrathyroidal NIS expression in lactating mammary tissue, gastric mucosa, and salivary gland, as well as studies of thyroid pathophysiology, hypothyroidism models, and TSH-mediated regulation of iodide transport under research use only conditions.