Rat sCD80 (Soluble Cluster of Differentiation 80) ELISA Kit (RTES01100)

CD80 (B7-1) is a 60 kDa transmembrane glycoprotein expressed on antigen-presenting cells. It delivers the essential second signal for T-cell activation through CD28 and counter-balances CTLA-4-mediated inhibition. The soluble form (sCD80) is shed from activated B cells, dendritic cells, and macrophages, and is detectable in circulation at elevated levels during inflammation, autoimmune flare, allograft rejection, and certain malignancies. This Assay Genie kit provides a quantitative in vitro method for measuring sCD80 in rat research samples, supporting studies on immune regulation, transplantation tolerance, and inflammatory disease models. The microplate arrives pre-coated with a capture antibody, with all reagents supplied in single-use vials for a straightforward workflow. Store unopened components refrigerated; avoid freeze-thaw cycles to preserve antibody activity and aliquot working solutions where indicated.