Rat Receptor Interacting Serine Threonine Kinase 3 (RIPK3) ELISA Kit

This ELISA kit from Assay Genie enables quantitative measurement of Receptor Interacting Serine/Threonine Kinase 3 (RIPK3) in rat-derived specimens. RIPK3 is a critical serine/threonine kinase governing necroptosis, a caspase-independent form of programmed cell death implicated in acute kidney injury, neurodegenerative disease, viral infection responses, and chronic inflammatory disorders. Quantitative RIPK3 readouts help researchers map activation of the necroptotic axis, evaluate RIPK1-RIPK3-MLKL signaling, and compare pathway engagement across disease models and intervention groups.

The kit is validated for tissue homogenates, cell lysates, and similar samples harvested from rat models. The assay uses a colorimetric readout on a microplate format, providing absorbance-based quantification compatible with standard laboratory plate readers. Each kit contains all required reagents, including coated wells, detection antibody, standards, and buffers, supporting research applications in apoptosis and necroptosis pathway studies, toxicology screening, infectious disease modeling, and drug efficacy evaluation.

For handling, unopened kit components should be stored refrigerated and protected from light until first use; reconstituted reagents follow the conditions specified in the manual. The product is intended for research use only.