Rat PS1 (Presenilin 1) ELISA Kit (RTES01003)

The Presenilin 1 rat immunoassay kit from Assay Genie provides quantitative measurement of endogenous PS1 protein in experimental rat samples. Presenilin 1 functions as the catalytic core of the gamma-secretase complex, mediating cleavage of amyloid precursor protein and Notch receptors, and is a focal point of neuroscience research into Alzheimer's disease mechanisms, familial early-onset dementia, and gamma-secretase modulation.

Supporting both in vitro and in vivo research workflows, this microplate-based ELISA kit enables laboratories investigating PS1 expression in neural tissue, peripheral tissue samples, and disease-model rat strains. The assay delivers colorimetric readouts on standard plate readers, allowing straightforward integration into established laboratory protocols without specialized instrumentation.

Each kit is supplied with pre-coated wells, ready-to-use assay buffer, a detection antibody, standard reference protein, and complete protocol documentation. The plate layout supports standard curve generation alongside multiple experimental samples in a single run, making the kit practical for studies comparing PS1 levels across treatment cohorts, transgenic models, and time-course experiments.

Applications include neurodegenerative disease research, drug screening for gamma-secretase modulators, evaluation of transgenic rat phenotypes, and characterization of synaptic dysfunction associated with presenilin mutations. The product is intended for research use only and is not validated for diagnostic procedures.