Rat Protein Tyrosine Phosphatase, Non Receptor Type 11 (PTPN11) ELISA Kit

Quantitative rat PTPN11 enzyme measurement kit from Assay Genie quantifies SHP-2 non-receptor tyrosine phosphatase in tissue homogenate specimens. The PTPN11 gene encodes SHP-2, a critical regulator of RAS/MAPK and PI3K/AKT signal transduction pathways implicated in Noonan syndrome, LEOPARD syndrome, and juvenile myelomonocytic leukemia. Investigators apply this 96-assay kit to rat models examining developmental signaling, cardiac morphogenesis, and oncogenic transformation. The microplate-based procedure supports 96 determinations when samples are processed in duplicate, with all reagents supplied in a single kit. Specimens derive from tissue homogenates and related sample types prepared under standard laboratory protocols, intended for research use only.