Rat Protein Phosphatase, Mg2+/Mn2+ Dependent 1A (PPM1A) ELISA Kit

PPM1A (also known as PP2Cα) is a serine/threonine phosphatase requiring magnesium and manganese ions for catalytic activity. It plays a central regulatory role in TGF-β signaling through dephosphorylating Smad2 and Smad3, modulates p38 MAPK cascades under cellular stress, and represses CDK2 and CDK6 activity during cell cycle progression.

Researchers studying hepatotoxicity, myocardial ischemia, neurodegeneration, and inflammatory signaling pathways use this Assay Genie kit to quantify PPM1A protein expression in rat tissue homogenates and cell lysates. The kit provides pre-coated microplate wells, dilution buffers, detection antibody reagents, and chromogenic substrate for research use only applications.