Rat Prohibitin (PHB) ELISA Kit

Prohibitin is a highly conserved ~30 kDa protein that localizes to the inner mitochondrial membrane, the nucleus, and the plasma membrane, where it acts as a chaperone complex and signaling scaffold in mitochondrial biogenesis, oxidative phosphorylation regulation, cell cycle control, apoptosis, and cellular senescence. The Assay Genie Rat Prohibitin (PHB) ELISA Kit delivers a quantitative immunoassay built specifically for measuring this biomarker in rat-derived specimens.

This rat-specific ELISA kit accommodates a range of sample matrices including serum-based, plasma-derived, tissue homogenate, and cell lysate workflows. The plate is read on a standard microplate reader using an absorbance-based, colorimetric readout, and the kit supplies pre-coated wells, reference standards, and detection reagents for 96 determinations in a single-use plate format suited to medium-throughput studies.

Common research contexts include investigations of mitochondrial dysfunction in cardiac and neural tissues, metabolic syndrome and insulin resistance models, hepatic and renal injury studies, reproductive biology, tumor biology, and aging-related cellular decline, where prohibitin expression often shifts in response to oxidative stress and altered metabolic states.