Rat Presenilin 1 (PSEN1) ELISA Kit

Built for neuroscience and neurodegenerative disease research, this Presenilin 1 ELISA Kit from Assay Genie enables quantitative measurement of PSEN1 protein in rat specimens. Presenilin 1 serves as the catalytic core of the gamma-secretase complex, and mutations in the PSEN1 gene are among the most studied genetic causes of early-onset familial Alzheimer's disease.

Supplied as 96 assays per box, the kit supports medium-throughput experimental workflows in academic and pharmaceutical laboratories. Validated specifically for rat-derived samples, the assay accommodates multiple specimen matrices, allowing researchers to profile PSEN1 levels across both peripheral and central nervous system compartments in rat disease models.

Applications include profiling gamma-secretase activity, characterizing amyloid precursor protein cleavage, and examining how presenilin mutations shape neuronal signaling, synaptic plasticity, and cell viability. The kit is intended for in vitro research use only and fits studies of molecular neurodegeneration, age-related cognitive decline, and the cellular consequences of altered presenilin expression in rat systems.