Rat POU domain, class 3, transcription factor 4 (Pou3f4) ELISA Kit

From Assay Genie, this sandwich ELISA kit is designed for the precise measurement of POU domain, class 3, transcription factor 4 (Pou3f4) in rat samples. POU3F4 is a transcription factor that plays a critical role in inner ear development and hearing, and mutations in the POU3F4 gene are associated with X-linked deafness, making this assay relevant for research in auditory biology, genetics, and developmental biology.

The assay exhibits a detection range of 0.156-10 ng/mL with a sensitivity of 0.053 ng/mL, and shows specificity for natural and recombinant rat POU3F4. The target protein is located in the nucleus and has a reported molecular weight of 39,427 Da. According to the manufacturer, POU3F4 is a probable transcription factor which exerts its primary action widely during early neural development and in a very limited set of neurons in the mature brain.

The kit is suitable for use with serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, and uses a colorimetric detection method. Synonyms associated with this protein include Brain-specific homeobox/POU domain protein 4, Octamer-binding protein 9, Octamer-binding transcription factor 9, RHS2 class III POU protein, Brain-4, Oct-9, OTF-9, Brn-4, Brn4, and Otf9. The product is for research use only.