Rat Plasminogen Activator, Tissue (tPA) ELISA Kit

Tissue plasminogen activator (tPA) is a serine protease that drives the fibrinolytic cascade by converting plasminogen to plasmin, and the Assay Genie Rat tPA ELISA Kit quantifies this enzyme in rat plasma samples on a microplate format. The assay supports vascular biology, hemostasis, and stroke research using rat experimental models.

The kit contains reagents sufficient for 96 assays, including a precoated capture plate, recombinant rat tPA standards for generating a standard curve, detection reagents, wash buffer, and TMB substrate. The assay produces an absorbance signal proportional to tPA levels in experimental samples and is read on a standard microplate reader. Unopened kit components should be refrigerated according to the product insert to preserve reagent activity.

Researchers apply this kit to study fibrinolysis, thrombosis models, cerebral ischemia, stroke injury, and cardiovascular dysfunction in rats. It supports investigations of tPA release under pharmacological challenge, changes in plasma tPA across disease models, and interventions targeting the plasminogen activation system. For research use only.