Rat PHB (Prohibitin) CLIA Kit (RTES00468)

Quantitative Prohibitin Measurement in Rat Models

Prohibitin (PHB) is a ubiquitously expressed, highly conserved 30 kDa protein that localizes to mitochondria, the nucleus, and the plasma membrane, where it regulates mitochondrial respiratory function, cell cycle progression, and apoptotic signaling.

The Assay Genie Rat PHB CLIA Kit uses a chemiluminescence-based immunoassay format to quantify Prohibitin in rat-derived samples, providing the broad dynamic range and low background characteristic of luminescent detection methods.

Researchers use this 96-assay plate format to track PHB expression in rat models of cardiac hypertrophy, where prohibitin translocates between mitochondrial and nuclear compartments, in studies of granulosa cell apoptosis during follicular atresia, and in investigations of hepatic and renal injury, where altered PHB levels reflect mitochondrial stress.

Chemiluminescent readout supports quantitative comparisons between treatment groups in longitudinal rat studies, including metabolic disease, neurodegeneration, and aging research where mitochondrial dysfunction is a primary readout.