Rat Pepsinogen A (PGA) ELISA Kit

Quantitative measurement of pepsinogen A in rat-derived research samples is enabled by the Assay Genie Rat Pepsinogen A (PGA) ELISA Kit, which supplies reagents for 96 individual determinations per pack. Pepsinogen A is secreted by chief cells of the gastric mucosa as a zymogen precursor to pepsin, and circulating PGA levels are widely used in research as a non-invasive biomarker of gastric mucosal integrity and digestive disease. Investigators studying rat models of gastritis, peptic ulcer disease, gastric erosion, Helicobacter-associated pathology, or gastrointestinal pharmacology rely on serum PGA quantification to monitor mucosal damage and recovery over the course of an experiment. The workflow accepts tissue homogenates and supernatant fractions alongside serum, supporting both systemic circulation studies and localized gastrointestinal tract investigations. Each microplate-based run is read on a standard plate reader using an absorbance endpoint, and refrigerated storage between sessions preserves antibody binding activity and standard curve stability. The kit is for research use only and is intended for laboratory investigation of gastric physiology, digestive disease modeling, and pre-clinical drug response assessment in rats.