Rat Notch-2 PharmaGenie ELISA Kit (SBRS1684)

The Assay Genie Notch-2 immunoassay kit enables quantitative measurement of endogenous Notch-2 receptor protein in rat biological samples, supporting research into the Notch signaling pathway that governs cell fate decisions, vascular development, and hepatic differentiation.

Each kit provides pre-coated microplate wells, capture and detection antibodies, recombinant standards, and substrate reagents sufficient for one full plate run. Researchers typically load 100 µL of standard or unknown sample per well, then quantitate target binding after the enzymatic reaction step.

Notch-2 (Neurogenic locus notch homolog protein 2) is a single-pass transmembrane receptor that is proteolytically cleaved upon ligand binding, releasing the Notch intracellular domain to function as a transcriptional co-activator. Aberrant Notch-2 signaling has been linked to Alagille syndrome, Hajdu-Cheney syndrome, marginal zone B-cell lymphoma, and triple-negative breast cancer, so accurate protein quantitation in rat models is valuable for translational research.

For research use only. Store kit components refrigerated; consult the supplied protocol for reagent-specific handling, aliquot instructions, and shelf life guidance.