Rat Neutral Sphingomyelinase (NSMASE) ELISA Kit

Neutral sphingomyelinase (NSMASE) is a key enzyme in sphingolipid metabolism, catalyzing hydrolysis of sphingomyelin to generate ceramide, a lipid second messenger implicated in apoptosis, inflammation, oxidative stress responses, and membrane remodeling. This rat-specific quantification kit from Assay Genie is intended for research laboratories investigating ceramide signaling pathways, neuronal stress models, hepatic lipid studies, and cardiovascular injury mechanisms.

The kit provides reagents sufficient for 96 assays in a microplate format, using a colorimetric readout compatible with standard laboratory plate readers. It is reactive with rat samples, including tissue homogenates prepared from brain, liver, kidney, or vascular tissue. Researchers studying neurodegenerative disease models, ischemic injury, fatty liver pathophysiology, or pharmacological modulation of sphingolipid balance can use this kit to measure endogenous NSMASE activity levels across experimental conditions and treatment groups.

Each kit package contains a pre-coated microplate, assay buffers, detection reagents, and a standard curve of recombinant rat NSMASE for accurate interpolation of unknown samples. The product is intended for research use only and is not validated for diagnostic or clinical applications.