Rat Neuropeptide S (Nps) ELISA Kit

A competitive ELISA from Assay Genie designed for the quantitative measurement of neuropeptide S in rat samples. The assay has been validated for use with serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids, and is intended for research use only.

Reported performance specifications include a detection range of 0.156–10 ng/mL, a sensitivity of 0.082 ng/mL, an intra-assay CV of 4.6%, and an inter-assay CV of 7.7%. The kit shows specificity for natural and recombinant rat neuropeptide S. The target protein (UniProt P0C0P7) has a reported molecular weight of 9,763 Da.

Neuropeptide S is a secreted peptide that modulates arousal and anxiety and may play an important anorexigenic role. It binds to its receptor NPSR1 with nanomolar affinity to increase intracellular calcium concentrations, and dysregulation of the peptide has been linked to psychiatric disorders such as anxiety and depression, supporting its investigation as a potential biomarker in immunology-focused research.