Rat Natriuretic Peptide Receptor 2 (NPR2) ELISA Kit

Membrane-bound guanylyl cyclase receptors are central to cardiovascular, skeletal, and reproductive signaling, and the Assay Genie Rat Natriuretic Peptide Receptor 2 (NPR2) ELISA Kit delivers quantitative measurement of NPR2 in rat-derived specimens. Also referred to as NPR-B, this receptor binds C-type natriuretic peptide (CNP) and drives intracellular cGMP production in chondrocytes, vascular smooth muscle, and ovarian granulosa cells, making it a target of interest for studies of endochondral ossification, vascular remodeling, and oocyte meiotic arrest.

Supplied as 96 assays and validated for rat tissue homogenates, the kit provides a reproducible readout of receptor abundance across experimental cohorts. Investigators in skeletal biology, cardiovascular pharmacology, and reproductive endocrinology apply NPR2 measurements to characterize CNP ligand engagement, downstream cyclic GMP flux, and disease-linked receptor variants such as those implicated in acromesomelic dysplasia, Maroteaux-type short stature, and idiopathic growth failure.

Each Assay Genie NPR2 kit includes the reagents required to complete the run and is intended for research use only. Users should be familiar with plate-based ELISA workflows and standard biosafety handling of animal-derived tissue samples.