Rat N-Acetyltransferase 2 (NAT2) ELISA Kit

This sandwich-style immunoassay from Assay Genie quantitatively detects rat N-acetyltransferase 2 (NAT2) enzyme levels in prepared tissue homogenates and other body-fluid samples, supporting pharmacology, toxicology, and pharmacogenomics research. NAT2 catalyzes the transfer of acetyl groups from acetyl-CoA to arylamines and hydrazines, a phase II conjugation reaction central to xenobiotic processing in the liver. Investigators studying interindividual variation in drug acetylation capacity, caffeine and isoniazid clearance kinetics, or aromatic amine carcinogen bioactivation use this kit to profile enzyme expression across rat tissues. The assay follows an in vitro protocol with a microplate-based absorbance readout, providing 96 individual determinations per kit. Intended for research use only, the reagents are configured for rat-specific reactivity and support laboratory investigation of metabolic enzyme regulation, gene polymorphism effects, and chemically induced changes in hepatic and extrahepatic acetylation activity.