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Rat MMP-14 (Matrix Metalloproteinase 14) ELISA Kit (RTES01049)
  • Rat MMP-14 (Matrix Metalloproteinase 14) ELISA Kit (RTES01049)
Assay Genie

Rat MMP-14 (Matrix Metalloproteinase 14) ELISA Kit (RTES01049)

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RTES01049

Price on request

Description

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MMP-14, also designated MT1-MMP, is a membrane-anchored matrix metalloproteinase that cleaves components of the extracellular matrix and activates other MMP zymogens, positioning it as a key target in studies of tumor cell invasion, angiogenesis, cartilage erosion, and vascular remodeling. Assay Genie's rat-specific immunoassay kit is built for quantitative measurement of this enzyme in samples from laboratory rats and is supplied as a microplate-based reagent set that supports up to 96 determinations per run, a throughput well matched to cohort-scale studies.

The kit is validated for reactivity with rat-derived samples, including rat serum, rat plasma, tissue homogenates, and conditioned media from cultured rat cells. Detection relies on an absorbance read-out on standard laboratory plate readers, enabling integration into existing immunology and biomarker workflows without specialized instrumentation. Each kit is shipped with capture and detection antibodies, a recombinant reference standard, substrate solution, and wash buffer, providing the reagents required to establish a standard curve and run matched internal controls.

Investigators working on rat models of breast cancer metastasis, post-infarct cardiac fibrosis, rheumatoid arthritis, or abdominal aortic aneurysm formation can apply this kit to quantify MMP-14 dynamics in longitudinal designs. The format is intended for research use only and is not cleared for diagnostic procedures.