Rat Mineralocorticoid Receptor (MR) ELISA Kit

Measuring mineralocorticoid receptor (MR) expression in rat-derived samples is straightforward with the Assay Genie ELISA Kit, configured for 96 individual determinations. The mineralocorticoid receptor is a ligand-activated transcription factor that mediates aldosterone and cortisol signaling, with central roles in sodium homeostasis, blood pressure regulation, and electrolyte balance. Studies of cardiovascular disease, hypertension, adrenal cortex function, and stress-axis biology all benefit from reliable MR quantification.

The kit is validated for tissue homogenates, cell lysates, and other rat-derived sample matrices. Each kit includes a pre-coated microplate, detection antibody, reference standards, wash buffer, and substrate solution sufficient for the full plate workflow. Researchers should store reagents according to the included protocol and bring all components to room temperature before running the assay. A standard microplate reader capable of measuring absorbance is required.

Applications include profiling MR levels in kidney, heart, brain, and adrenal tissues harvested from rat models. Investigators tracking receptor changes following aldosterone treatment, dietary salt manipulation, or genetic knockout studies can use the assay for comparative analysis across treatment groups. The kit is intended for research use only and is not validated for diagnostic or clinical procedures.