Rat Microsomal Glutathione S Transferase 1 (MGST1) ELISA Kit

MGST1 (Microsomal Glutathione S-Transferase 1) is a membrane-bound phase II detoxification enzyme anchored in the endoplasmic reticulum that catalyzes conjugation of reduced glutathione to electrophilic xenobiotics and lipid peroxidation products. The Assay Genie kit provides quantitative measurement of rat MGST1 protein in research workflows spanning toxicology, pharmacology, and oxidative stress biology.

Each kit is supplied with a pre-coated microplate, biotinylated detection antibody, streptavidin-HRP conjugate, reference standards, wash buffer, and substrate solution. Reconstituted components should be refrigerated at 4°C and protected from light; the plate should remain sealed inside its desiccant pouch to prevent moisture damage during storage.

MGST1 expression profiling is widely applied in hepatic and renal injury studies, where elevated levels reflect increased glutathione conjugation demand under xenobiotic challenge. Common research applications include evaluation of acetaminophen-induced hepatotoxicity, environmental pollutant exposure, and glutathione pathway modulation in rat disease models.