Rat Matrix Metalloproteinase 3 (MMP3) ELISA Kit

The Assay Genie rat MMP3 immunoassay provides researchers with a quantitative tool for measuring stromelysin-1 concentrations in rat-derived samples, supporting investigations into extracellular matrix turnover, joint degradation pathways, and inflammatory responses. MMP3, a zinc-dependent endopeptidase, cleaves a broad substrate spectrum including proteoglycans, fibronectin, and collagen types III, IV, and IX, making its quantification valuable for studies of osteoarthritis, rheumatoid arthritis progression, and cardiovascular remodeling.

The kit is configured as a 96 assays microplate format with a measurement readout compatible with standard laboratory plate readers. Researchers apply this assay to liquid specimens collected from rat models, including circulating blood fractions, with additional specimen types analyzable following appropriate validation. Each kit contains pre-coated wells, detection reagents, and a standard curve calibrator set calibrated to deliver reproducible measurements across runs. Reagents should be stored refrigerated to preserve activity until first use.

Beyond arthritis research, rat MMP3 quantification supports toxicology investigations, wound healing models, and studies of tumor microenvironment dynamics. The MMP3 protein serves as both a marker of cartilage breakdown and an indicator of activated synovial fibroblasts, giving the assay broad relevance in translational pharmacology and disease mechanism research. Intended for research use only, the kit integrates into workflows studying connective tissue pathology, biomarker discovery, and preclinical drug evaluation in rodent model systems.