Rat Linker For Activation Of T-Cell (LAT) ELISA Kit

Quantitative measurement of the transmembrane adapter protein LAT, central to T-cell receptor signaling, is enabled by the Assay Genie Rat Linker for Activation of T-Cell (LAT) ELISA Kit. Upon TCR engagement, LAT is phosphorylated by ZAP-70 and recruits downstream effectors driving lymphocyte activation, calcium flux, and cytokine production.

Built for immunology and signal transduction research, this immunoassay analyzes multiple specimen types from rat samples, including tissue homogenates, cell lysates, and cell culture supernatants. Researchers investigating T-cell maturation, immune synapse assembly, thymic selection, or autoimmune disease models can apply this kit to pathway-level studies, treatment comparisons, in vivo disease models, and ex vivo stimulation experiments.

Each package provides reagents for 96 assays in a colorimetric microplate format, comprising pre-coated wells, detection reagents, and buffer diluents. Intended for research use only, the kit integrates into standard workflows across academic and pharmaceutical immunology laboratories.