Rat Lig1/DNA ligase 1 ELISA Kit

From Assay Genie, this Sandwich ELISA Kit is intended for the quantitative detection of DNA Ligase 1 (LIG1) levels in rat samples, supporting research applications where high sensitivity and specificity are required. DNA Ligase 1 is described as an enzyme involved in DNA replication and repair processes, contributing to the maintenance of genomic stability, and its dysregulation has been linked to various diseases, making it a biomarker of interest for studying those conditions and exploring potential therapeutic interventions.

Detection is colorimetric, and the kit is validated for use with serum, plasma, cell culture supernatant, cell or tissue lysate, and other liquid samples. Reported performance includes a sensitivity of 46.875 pg/mL and a working range of 78.125-5000 pg/mL. The kit is intended for storage at 2-8°C for 12 months. Reported recovery is 88-104% (average 97%) for serum, 90-105% (average 100%) for EDTA plasma, and 86-104% (average 95%) for heparin plasma.