Rat JNK1/MAPK8 Associated Membrane Protein (JKAMP) ELISA Kit

The JKAMP target encoded by the Jkamp gene is a JNK1-associated integral membrane protein anchored in the endoplasmic reticulum, where it modulates c-Jun N-terminal kinase signaling and contributes to proteasome-mediated protein quality control. This Assay Genie immunoassay is specifically validated for rat samples with no significant cross-reactivity to mouse or human orthologs, allowing investigators to quantify JKAMP levels in rat tissue homogenates during studies of ER stress, inflammatory signaling, and MAPK cascade crosstalk. Reconstituted standards and detection antibody should be stored frozen in single-use aliquots to limit freeze-thaw degradation, while the sealed kit components remain refrigerated for the duration of their shelf life; protect the substrate solution from light to maintain stable signal output. For confirmatory work, researchers commonly pair the assay with western blot or immunohistochemistry to validate subcellular distribution and pathway activation in rat model systems.