Rat Jagged 1 PharmaGenie ELISA Kit (SBRS1669)

Quantitative measurement of Jagged 1 (JAG1) protein levels in rat experimental specimens is supported by this ELISA Kit from Assay Genie, intended for research use only. JAG1 is a transmembrane ligand for Notch receptors, driving cell-cell communication involved in angiogenesis, hematopoietic stem cell maintenance, vascular smooth muscle differentiation, and bile duct development. Dysregulation of JAG1-Notch signaling has been implicated in Alagille syndrome, cardiovascular remodeling, and certain leukemias, making this assay broadly applicable across developmental biology, hepatic research, and immunology studies.

Each kit supplies reagents sufficient for 96 determinations using a pre-coated microplate format. The procedure accommodates cell culture supernatant along with plasma or serum fractions collected from rat specimens. Included reagent components comprise lyophilized standard calibrators, a biotinylated detection antibody, streptavidin-HRP conjugate, concentrated wash buffer, and TMB substrate solution. Researchers working in vascular biology, hepatic bile duct morphogenesis, and Notch pathway laboratories apply this reagent for pathway activity profiling, target validation experiments, and biomarker investigation in rodent disease models. The product is labeled for research use only and is not validated for diagnostic or clinical use.