Rat IL-4r ELISA Kit (RTEB1331)

This Sandwich ELISA Kit from Assay Genie is designed for the quantitative detection of rat Interleukin-4 receptor subunit alpha (IL-4r), also referred to by the synonyms CD124 and Il4ra. The assay uses a colorimetric detection method in a solid phase plate format.

The kit reports a detection range of 31.2-2000pg/mL and a sensitivity of 15.82pg/mL, with specificity for natural and recombinant rat Interleukin-4 receptor subunit alpha. Validated sample types include serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, with additional preparation procedures described for cell lysates, urine, cerebrospinal fluid and breast milk.

IL-4r acts as a receptor for both interleukin-4 and interleukin-13, coupling to the JAK-STAT signalling pathway and contributing to Th2 differentiation, IgE regulation and responses at sites of allergic inflammation. The soluble isoform 2 is reported to inhibit IL4-induced spleen cell proliferation. The research area is immunology, the UniProt reference for the target protein is Q63257, and the listed molecular weight is 25.1kDa. Kit reagents are stored at -20°C and shipped at +4°C, and the product is intended for research use only.