Rat HFE2 (uvenile-uman homolog) ELISA Kit (RTES01202)

HFE2, also known as hemojuvelin (HJV) or RGMc, is a key regulator of hepatic hepcidin expression and systemic iron homeostasis. Mutations in HFE2 are linked to juvenile hemochromatosis, a severe iron-overload disorder. This immunoassay from Assay Genie enables quantitative measurement of circulating HFE2 protein in rat specimens, supporting research into iron-metabolism disorders, anemia of inflammation, and hepatic iron-loading models. The kit includes a pre-coated microplate, biotin-conjugated detection antibody, streptavidin-HRP reagents, a calibrated standard, and dilution buffers. Store unopened components refrigerated; the standard should be aliquoted and frozen at -20°C for long-term stability. Researchers commonly apply this ELISA to investigate hepcidin pathway dynamics in rodent models of dietary iron deficiency, phlebotomy studies, and inflammatory cytokine challenge.