Rat Heat shock protein beta-6 (Hspb6) ELISA Kit

From Assay Genie, this sandwich ELISA kit is designed for the quantitative measurement of Heat shock protein beta-6 (Hspb6), also referred to as Heat shock 20 kDa-like protein p20 or HspB6, in rat samples. The assay detects natural and recombinant rat HSPB6 and is intended for research use only, supporting studies of this small heat shock protein in the cellular stress response and in maintaining protein homeostasis.

Using a colorimetric sandwich ELISA format, the kit reports a sensitivity of 0.335ng/mL and a detection range of 0.625-40ng/mL. Compatible sample types include serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. The associated UniProt accession for the target protein is P97541.

HSPB6 functions as a molecular chaperone that helps to maintain denatured proteins in a folding-competent state, and is described as playing versatile roles across multiple biological processes. Reported functions include the regulation of smooth muscle vasorelaxation and cardiac myocyte contractility, involvement in myocardial angiogenesis implicating KDR, and the mediation of cardioprotection and angiogenesis following induced damage, as well as stabilising monomeric YWHAZ to support its chaperone-like activity. The kit is designated for cancer research and for broader investigations into stress-related cellular biology.