Rat HDAC2 (Histone Deacetylase 2) ELISA Kit (RTES00813)

Histone Deacetylase 2 (HDAC2) is a class I chromatin-modifying enzyme that catalyzes the removal of acetyl groups from lysine residues on histone and non-histone protein substrates, contributing to chromatin compaction, transcriptional repression, and the regulation of cell cycle progression, neuronal plasticity, and inflammatory signaling. Quantification of HDAC2 abundance in rat model systems is supported by the Assay Genie Rat HDAC2 ELISA Kit, an absorbance-based microplate immunoassay supplied as a complete reagent kit for research use only.

Altered HDAC2 expression has been documented in studies of neurodegeneration, cardiac hypertrophy, chronic inflammation, and tumor cell proliferation, and researchers commonly apply such assays to compare control and treated cohorts, monitor pharmacodynamic responses to small-molecule HDAC inhibitors, and correlate enzyme levels with downstream transcriptional or behavioral readouts. The kit is formatted for processing on standard microplates, with all required reagents provided for the immunoassay workflow.

It is intended for use with rat-derived sample matrices such as serum and tissue homogenates. Samples should be collected and processed under standard laboratory conditions, and assay components should be handled according to the accompanying product insert. The kit is supplied in a single use configuration, and absorbance readings are obtained on a compatible microplate reader. For exact performance characteristics such as detection limits and dynamic range, researchers should consult the lot-specific certificate of analysis provided with the kit.